Lipid mediator abundance in skeletal muscle of BALB/C mouse with and without C26-induced cancer cachexia

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Provided by Catholic University of Leuven

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Dataset information

Catalog

Catholic University of Leuven catalog

Country of origin

Belgium

Updated

2026.01.30 13:46

Created

2026.01.30

Available languages

English

Keywords

endocannabinoid system, Skeletal muscle, cancer cachexia

Datasource

Official portal for European data link

Quality scoring

Dataset description

This study investigated whether cancer affected the muscle lipid mediator abundance. Male BALB/c mice were injected with PBS (CON) or C26 colon carcinoma cells (C26) (n = 5/group). Mice were sacrificed 18 days upon PBS/tumor cell injection. The relative abundance of lipid mediators was analyzed in the vastus medialis muscle (~15mg; part of m. Quadriceps). Lipid extraction and the LC-MS/MS–based lipidomics was performed by the KU Leuven Lipometrix core facility. More detail is provided by Dalle, S., Hiroux, C., & Koppo, K. (2024). Endocannabinoid remodeling in murine cachexic muscle associates with catabolic and metabolic regulation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1870(5), 167179. https://doi.org/10.1016/j.bbadis.2024.167179

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