The PI-CAI Challenge: Public Training and Development Dataset

This dataset represents the PI-CAI: Public Training and Development Dataset. It contains 1500 anonymized prostate biparametric MRI scans from 1476 patients, acquired between 2012-2021, at three centers (Radboud University Medical Center, University Medical Center Groningen, Ziekenhuis Groep Twente) based in The Netherlands. The PI-CAI challenge is an all-new grand challenge that aims to validate the diagnostic performance of artificial intelligence and radiologists at clinically significant prostate cancer (csPCa) detection/diagnosis in MRI, with histopathology and follow-up (≥ 3 years) as the reference standard, in a retrospective setting. The study hypothesizes that state-of-the-art AI algorithms, trained using thousands of patient exams, are non-inferior to radiologists reading bpMRI. Key aspects of the PI-CAI study design have been established in conjunction with an international scientific advisory board of 16 experts in prostate AI, radiology and urology —to unify and standardize present-day guidelines, and to ensure meaningful validation of prostate AI towards clinical translation (Reinke et al., 2021).