Data for: Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis

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Provided by Linköpings universitet

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Dataset information

Catalog

Linköpings universitet catalog

Country of origin

Sweden

Updated

2025.07.04 09:51

Created

2023.09.22

Available languages

English

Keywords

Proteomics, Proteomik, Multipel skleros, Multiple sclerosis

Datasource

Official portal for European data link

Quality scoring

Dataset description

The concentration of 1463 proteins were measured using the Olink Explore platform which uses Proximity Extension Assay (PEA) technology. The proteins are preselected from four Olink panels: Explore 384 Cardiometabolic, Explore 384 Inflammation, Explore 384 Neurology, and Explore 384 Oncology. The protein concentrations are given as Olink’s relative protein quantification unit on log2 scale: Normalized Protein Expression (NPX). The NPX values were intensity normalized by Olink. Protein levels were measured in cerebrospinal fluid samples (n = 186) and plasma samples (n = 165) from persons with multiple sclerosis and healthy controls. The dataset was originally published in DiVA and moved to SND in 2024.

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2019

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