Ex-vivo Drug Responses and Molecular Genetic Profiles of 597 Pediatric ALL Patients

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Provided by Uppsala universitet

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Dataset information

Catalog

Uppsala universitet catalog

Country of origin

Sweden

Updated

2024.06.25 00:00

Created

2024.06.25

Available languages

English

Keywords

Oncology and carcinogenesis not elsewhere classified, Epigenetics (incl. genome methylation and epigenomics)

Datasource

Official portal for European data link

Quality scoring

Dataset description

This dataset contains genome-wide DNA methylation data generated from 55 pediatric acute lymphoblastic leukemia (ALL) samples originating from bone marrow or peripheral blood samples taken at ALL diagnosis (n = 55). Genome-wide DNA methylation was analyzed at the SNP&SEQ Technology Platform, SciLifeLab, National Genomics Infrastructure Uppsala, Sweden. Per sample, 250 ng of genomic DNA was bisulfite converted using EZ DNA MethylationTM Kit from Zymo Research. The bisulfite converted DNA was eluted in 15μl according to the manufacturer´s protocol, evaporated to a volume of

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